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Proliferative vitreoretinopathy

MONDO:0700115

Vitreoretinal membrane shrinkage or contraction secondary to the proliferation of primarily retinal pigment epithelial cells and glial cells, particularly fibrous astrocytes, followed by membrane formation. The formation of fibrillar collagen and cellular proliferation appear to be the basis for the contractile properties of the epiretinal and vitreous membranes.

18 clinical trials for this condition and its sub-types.

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Sub-types

CAPN5-related vitreoretinopathy (0)

Broader categories

Disease (680) Nervous system disorder (231) Eye disorder (102) Retinal disorder (85) Human disease (14) Disorder of orbital region (3) Disorder of visual system (1) Disease by body system or component (0)
Trials to join now! 7 Not yet recruiting 3 Not yet finished but already full! 1 Completed 6 Terminated 1
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  • AI eye scans aim to predict Sight-Threatening complication after retinal surgery

    Knowledge-focused ENROLLING_BY_INVITATION

    This study investigates whether advanced eye imaging and artificial intelligence can predict proliferative vitreoretinopathy (PVR), a condition that can cause retinal detachment surgery to fail. Researchers will analyze scans from 100 patients with retinal detachment, some with P…

    Sponsor: University College, London • Aim: Knowledge-focused

    Last updated Jul 04, 2026 00:00 UTC

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