Primary pigmented nodular adrenocortical disease
MONDO:0015999A form of bilateral adrenocortical hyperplasia that is often associated with adrenocorticotrophin hormone (ACTH) independent Cushing syndrome and is characterized by small to normal sized adrenal glands containing multiple small cortical pigmented nodules (less than 1 cm in diameter).
Also known as: PPNAD, pigmented nodular adrenocortical disease, pigmented nodular adrenocortical disease, primary, primary pigmented nodular adrenal dysplasia
10 clinical trials for this condition and its sub-types.
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Scientists uncover genetic secrets behind rare hormone disorders
Knowledge-focused CompletedThis study looked at nearly 1,400 people with rare conditions like PPNAD, Carney Complex, and Peutz-Jeghers syndrome. The goal was to find the genetic causes and link them to specific symptoms. Researchers used clinical exams and genetic testing to better understand how these dis…
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) • Aim: Knowledge-focused
Last updated Jul 04, 2026 00:00 UTC
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Researchers measure breathing, strength, and quality of life in hospitalized endocrine patients
Knowledge-focused CompletedThis completed observational study at Uşak University examined 150 adults hospitalized in the endocrinology department. Researchers measured breathing, muscle strength, pain, fatigue, sleep quality, physical activity, balance, and nerve function. The goal was to better understand…
Sponsor: Uşak University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Researchers track rare hormone disorder in 133 patients
Knowledge-focused CompletedThis study followed 133 people with PPNAD (a rare adrenal gland disorder) or Carney Complex (a related genetic condition) for three years. The goal was to better understand the symptoms and genetic causes of these diseases, not to test a new treatment. Participants had yearly che…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC