Postlingual non-syndromic genetic hearing loss
MONDO:0016298Postlingual non-syndromic genetic deafness is a rare, genetically highly heterogeneous otorhinolaryngologic disease, resulting from inner and/or middle ear or hearing nerve anomalies, typically characterized by progressive, bilateral, moderate to profound hearing loss (mean sensorineural hearing impairment equal to 40 dB or more for 500-, 1,000-, and 2,000-Hz frequency tones in the better ear) which occurs after the onset of speech development and is not associated with visible external ear abnormalities or any other medical problems. Language development is not initially significantly delayed.
Also known as: isolated postlingual genetic deafness, postlingual non-syndromic genetic deafness
10 clinical trials for this condition and its sub-types, 6 tagged with Postlingual non-syndromic genetic hearing loss itself.
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Browse by category →Sub-types of Postlingual non-syndromic genetic hearing loss
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Deafness, aminoglycoside-induced 4 trials
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Mapping the brain's adaptation to cochlear implants in the first year
Knowledge-focused Recruiting nowThis study follows adults who have recently received a cochlear implant to track how their ability to distinguish sounds and understand speech changes over time. Participants complete at-home sound tests frequently during the first three months, then return for lab tests up to on…
Sponsor: NYU Langone Health • Aim: Knowledge-focused
Last updated Jul 03, 2026 00:00 UTC
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Hearing loss linked to brain fog in middle age?
Knowledge-focused Recruiting nowThis study compares cognitive function in 180 adults aged 45-64 with severe hearing loss to those with normal hearing. Participants take memory, attention, and thinking tests. The goal is to see if hearing loss is linked to mild cognitive impairment earlier in life.
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:57 UTC