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Periodic fever-infantile enterocolitis-autoinflammatory syndrome

MONDO:0014472

Also known as: Autoinflammation with Infantile Enterocolitis, NLRC4-related MAS, NLRC4-related autoinflammatory syndrome with MAS, NLRC4-related autoinflammatory syndrome with macrophage activation syndrome, NLRC4-related infantile enterocolitis-autoinflammatory syndrome, NLRC4-related macrophage activation syndrome, autoinflammation with infantile enterocolitis, AIFEC

14 clinical trials for this condition and its sub-types.

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Broader categories

Disease (680) Hereditary disease (176) Rheumatic disorder (87) Connective tissue disorder (68) Syndromic disease (25) Autoinflammatory syndrome (21) Human disease (14) Hereditary periodic fever syndrome (5) Disease of genetic or genomic mechanism (2) Periodic fever syndrome (2)
Trials to join now! 8 Not yet recruiting 2 Not yet finished but already full! 1 Completed 3
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  • New drug aims to tame rare immune storms

    Disease control Ongoing

    This phase 2 study tests a drug called MAS825 in 17 people with rare genetic conditions that cause severe inflammation. The goal is to see if the drug can prevent disease flares better than a placebo. Participants will be monitored for safety and effectiveness over several period…

    Phase: PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control

    Last updated Aug 02, 2026 00:00 UTC

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