Patent ductus arteriosus
MONDO:0011827A congenital defect characterized by the failure of the ductus arteriosus to close soon after birth. As a consequence, blood from the aorta mixes with blood from the pulmonary artery. If untreated, it may lead to congestive heart failure.
Also known as: PDA, patent ductus arteriosus, patent ductus botalli, persistent patency of the arterial duct, patency of the ductus arteriosus, patent ductus arteriosus familial (type)
102 clinical trials for this condition and its sub-types, 28 tagged with Patent ductus arteriosus itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Patent ductus arteriosus
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Char syndrome 0 trials
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PDA1 0 trials
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Patent ductus arteriosus 2 0 trials
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Patent ductus arteriosus 3 0 trials
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Can brain and gut artery scans guide heart treatment in premature babies?
Diagnosis Not yet recruitingResearchers are testing whether adding organ Doppler ultrasound to standard echocardiography helps doctors better manage a common heart vessel problem in preterm infants. The trial enrolls 88 premature babies born before 34 weeks or weighing under 1800 grams. Half receive standar…
Sponsor: Assiut University • Aim: Diagnosis
Last updated Sep 12, 2026 00:00 UTC
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Heart defect closure study seeks to reveal hidden remodeling
Knowledge-focused Not yet recruitingThis study looks at how the heart's upper and lower chambers change shape and function after closing a hole called patent ductus arteriosus (PDA) using a catheter-based procedure. It will include 40 people aged 12 and older who are already scheduled for the closure. The goal is t…
Sponsor: Emil Magdy Badry • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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New study aims to personalize care for tiny hearts
Knowledge-focused Not yet recruitingThis study focuses on extremely preterm infants (born before 32 weeks) who have a heart condition called hsPDA. Researchers will collect blood samples and health data to create a model that predicts which infants need treatment. They are also developing a targeted drug-delivery s…
Sponsor: Peking University Third Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC