Pancreatic neuroendocrine tumor
MONDO:0019954Pancreatic endocrine tumor, also known as pancreatic neuroendocrine tumor (PNET), describes a group of endocrine tumors originating in the pancreas that are usually indolent and benign, but may have the potential to be malignant. They can be functional, exhibiting a hormonal hypersecretion syndrome, but can be non-functional presenting with non-specific symptoms and include insulinoma, glucagonoma, VIPoma, somatostatinoma (SSoma), PPoma and Zollinger-Ellison syndrome (ZES, or gastrinoma) and other ectopic hormone producing tumors (such as GRFoma).
Also known as: islet cell tumor, islet cell tumors - pancreas, islet cell tumors of the pancreas, islet cell tumour, islet cell tumours - pancreas, islet cell tumours of the pancreas, pancreatic NET, pancreatic neuroendocrine tumor
1556 clinical trials for this condition and its sub-types, 60 tagged with Pancreatic neuroendocrine tumor itself.
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Sub-types of Pancreatic neuroendocrine tumor
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Functional pancreatic neuroendocrine tumor 1 trial · 14 incl. sub-types
3 sub-types
- Pancreatic insulinoma 13 trials
- Pancreatic ACTH-producing neuroendocrine tumor 0 trials
- Pancreatic gastrinoma 0 trials
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Pancreatic insulin-producing neuroendocrine tumor 0 trials · 13 incl. sub-types
1 sub-type
- Pancreatic insulinoma 13 trials
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Somatostatinoma 6 trials
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Pancreatic neuroendocrine tumor G1 1 trial · 5 incl. sub-types
1 sub-type
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1 sub-type
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Glucagonoma 2 trials
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1 sub-type
- Pancreatic gastrinoma 0 trials
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PPoma 1 trial
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VIPoma 1 trial
2 sub-types
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GRFoma 0 trials
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2 sub-types
- Pancreatic non-functioning delta cell tumor 0 trials
- Pancreatic somatostatinoma 0 trials
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Zapping pancreatic tumors without surgery: a safer approach?
Disease control Not yet recruitingThis early study tests if a new, needle-based treatment using brief electric pulses can safely destroy certain pancreatic tumors without surgery. The treatment aims to spare healthy tissue nearby. About 12 adults with specific pancreatic cysts or low-grade tumors will be enrolled…
Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Could chemo after surgery stop pancreatic tumor return?
Disease control Not yet recruitingThis phase 3 trial tests whether adding chemotherapy after surgery can prevent aggressive pancreatic neuroendocrine tumors from coming back. About 300 patients will either receive active surveillance alone or 6 cycles of capecitabine-temozolomide pills plus surveillance. The stud…
Phase 3 • Sponsor: Gustave Roussy, Cancer Campus, Grand Paris • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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Doctors watch and learn: new study tracks endoscopy for pancreatic disease diagnosis
Knowledge-focused Not yet recruitingThis study will watch how doctors use a special camera (endoscopic ultrasound) to diagnose suspected pancreatic or bile duct diseases in 2500 adults across Lombardy, Italy. The goal is to see how accurate the procedure is, how safe it is, and how quickly patients get a final diag…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Sep 05, 2026 00:00 UTC