Optic neuritis

MONDO:0005885

Optic neuritis is inflammation of the optic nerve, the nerve that carries the visual signal from the eye to the brain.The conditionmay cause sudden, reduced vision in the affected eye(s). While the cause of optic neuritis is unknown, it has been associated with autoimmune diseases, infections, multiple sclerosis, drug toxicity and deficiency of vitamin B-12. Vision often returns to normal within 2-3 weeks without treatment. In some cases, corticosteroids are given to speed recovery. If known, the underlying cause should be treated.

30 clinical trials for this condition and its sub-types, 21 tagged with Optic neuritis itself.

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Where it sits in the disease tree

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Part of

↑ Eye disorder (3079) ↑ Encephalomyelitis (227) ↑ Optic nerve disorder (96)

Sub-types of Optic neuritis

Optic papillitis 5 trials
1 sub-type
- Neuroretinitis 0 trials
Autoimmune optic neuritis 0 trials
Retrobulbar neuritis 0 trials
1 sub-type
- Acute retrobulbar neuritis 0 trials
Toxic optic neuropathy 0 trials
Toxic or nutritional optic neuropathy 0 trials

Including sub-types (30) Tagged with Optic neuritis (21)

Trials to join now! 9 Not yet recruiting 2 Not yet finished but already full! 2 Completed 7 Terminated 1

Herbal supplement fails to show clear benefit in optic neuritis pilot

Disease control Stopped early

This small pilot study tested whether adding gypenosides (a herbal supplement) to standard steroid treatment could help protect the nerve at the back of the eye in adults having their first episode of acute optic neuritis. Ten participants were enrolled, but the study was stopped…

Phase 2 • Sponsor: First Affiliated Hospital of Guangxi Medical University • Aim: Disease control

Last updated Jun 27, 2026 12:35 UTC

Optic neuritis

Where it sits in the disease tree

Herbal supplement fails to show clear benefit in optic neuritis pilot