Obesity-hypoventilation syndrome
MONDO:0009763Hypoventilation syndrome in very obese persons with excessive adipose tissue around the abdomen and diaphragm is characterized by diminished to absent ventilatory chemoresponsiveness; chronic hypoxia; hypercapnia; polycythemia; and long periods of sleep during day and night (hypersomnolence). It is a condition often related to obstructive sleep apnea but can occur separately.
Also known as: obesity-hypoventilation syndrome, Pickwickian syndrome
9 clinical trials for this condition and its sub-types.
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Could early CPAP help sleep apnea patients while they wait for a diagnosis?
Symptom relief Not yet recruitingThis study looks at whether starting CPAP therapy early for people with suspected obstructive sleep apnea (OSA) can improve their daytime sleepiness and quality of life while they wait for a formal sleep study. Participants are adults with strong signs of OSA, such as loud snorin…
Sponsor: Assiut University • Aim: Symptom relief
Last updated Jul 11, 2026 00:00 UTC
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Hypercapnic burden in adults with obesity undergoing diagnostic polysomnography for suspected obstructive sleep apnea: a prospective observational cohort study
Not yet recruitingObesity-related sleep hypoventilation represents a continuum ranging from isolated nocturnal hypoventilation to obesity hypoventilation syndrome. Current diagnostic criteria rely mainly on dichotomous thresholds and may not adequately reflect cumulative nocturnal carbon dioxide e…
Sponsor: Hospices Civils de Lyon
Last updated Sep 09, 2026 17:00 UTC