Neuromyelitis optica
MONDO:0019100A rare inflammatory disease of the central nervous system characterized mainly by attacks of uni- or bilateral optic neuritis (ON) and acute myelitis.
Also known as: Devic disease, Neuromyelitis Optica Spectrum Disorder, Devic syndrome, Devic's neuromyelitis optica, NMO
80 clinical trials for this condition and its sub-types.
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Broader categories
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Experimental pill for rare nerve disease shows early promise in tiny trial
Disease control TerminatedThis early-phase trial tested the drug zanubrutinib in just 6 adults with neuromyelitis optica spectrum disorder (NMOSD), a rare condition where the immune system attacks the nerves. Participants took the pill twice daily for a year to see if it could prevent relapses. However, t…
Phase: PHASE2 • Sponsor: Xuanwu Hospital, Beijing • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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New drug aims to stop relapses in rare brain disease
Disease control TerminatedThis study tested an experimental drug called RC18 in 178 people with neuromyelitis optica spectrum disorders (NMOSD), a rare disease that causes inflammation in the eyes and spinal cord. The goal was to see if RC18 could prevent relapses and slow disability. Participants had to …
Phase: PHASE3 • Sponsor: RemeGen Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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Russian NMOSD patients under the microscope: no new drug, just Real-World data
Knowledge-focused TerminatedThis study is not testing a new treatment. Instead, it observes how 100 adults with a rare autoimmune disease called NMOSD are managed in everyday Russian clinics. Researchers will collect medical records and follow patients over time to understand their symptoms, treatments, and…
Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated Jul 23, 2026 00:00 UTC