Neuromyelitis optica
MONDO:0019100A rare inflammatory disease of the central nervous system characterized mainly by attacks of uni- or bilateral optic neuritis (ON) and acute myelitis.
Also known as: Devic disease, Neuromyelitis Optica Spectrum Disorder, Devic syndrome, Devic's neuromyelitis optica, NMO
81 clinical trials for this condition and its sub-types.
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Broader categories
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Experimental pill for rare nerve disease shows early promise in tiny trial
Disease control TerminatedThis early-phase trial tested the drug zanubrutinib in just 6 adults with neuromyelitis optica spectrum disorder (NMOSD), a rare condition where the immune system attacks the nerves. Participants took the pill twice daily for a year to see if it could prevent relapses. However, t…
Phase: PHASE2 • Sponsor: Xuanwu Hospital, Beijing • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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New drug aims to stop relapses in rare brain disease
Disease control TerminatedThis study tested an experimental drug called RC18 in 178 people with neuromyelitis optica spectrum disorders (NMOSD), a rare disease that causes inflammation in the eyes and spinal cord. The goal was to see if RC18 could prevent relapses and slow disability. Participants had to …
Phase: PHASE3 • Sponsor: RemeGen Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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VR headsets tested as a possible treatment for blindness
Disease control TerminatedThis study tested whether using a virtual reality headset for one-hour sessions could help regenerate damaged optic nerves and improve vision in people with glaucoma or other retinal diseases. The idea came from promising results in rodents. However, the trial was terminated earl…
Phase: NA • Sponsor: Stanford University • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC