Neural tube defects, susceptibility to
MONDO:0020705Also known as: neural tube defects, spina bifida, susceptibility to, NTD, neural tube defects, SUSCEPTIBILITY to, spina bifida
10 clinical trials for this condition and its sub-types.
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Womb surgery breakthrough: two methods to fix spina bifida before birth
Disease control OngoingThis study tests two ways to surgically repair spina bifida in the womb using a tiny camera. The goal is to close the spinal defect and reverse brain changes caused by the condition. About 110 pregnant women carrying babies with spina bifida will take part. The two methods are co…
Phase: NA • Sponsor: University of Southern California • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Keyhole surgery in the womb could fix spina bifida with fewer risks
Disease control OngoingThis study tests a minimally invasive fetoscopic surgery to repair spina bifida in unborn babies. The goal is to close the spinal defect and reverse brain herniation while reducing risks like uterine rupture and preterm birth that come with open fetal surgery. Thirty pregnant wom…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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Patch may boost fetal spina bifida repair, early trial hints
Disease control OngoingThis study tests two minimally invasive fetal surgery techniques for repairing neural tube defects (spina bifida) in the womb. One method uses a Durepair patch to reinforce the repair, while the other does not. Researchers aim to see if the patch leads to a thicker repair and few…
Phase: PHASE1 • Sponsor: Baylor College of Medicine • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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Quick genetic test for unborn babies hits a snag: study withdrawn
Knowledge-focused TerminatedThis study aimed to see if a rapid whole genome sequencing test on amniotic fluid could give faster genetic diagnoses for fetuses with suspected genetic diseases. Researchers planned to compare results from amniotic fluid and blood samples from up to 90 families. However, the stu…
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:00 UTC