Neural tube defect
MONDO:0018075A congenital defect characterized by failure of the neural tube to close completely; this results in the presence of openings in the brain or spinal cord. Examples of neural tube defects include encephalocele and spina bifida.
Also known as: NTD, spinal dysraphism
24 clinical trials for this condition and its sub-types, 12 tagged with Neural tube defect itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Neural tube defect
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Chiari malformation type I 9 trials
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Primary tethered cord syndrome 2 trials
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Caudal regression sequence 1 trial
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Diastematomyelia 0 trials
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Iniencephaly 0 trials
2 sub-types
- Closed iniencephaly 0 trials
- Open iniencephaly 0 trials
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Isolated amyelia 0 trials
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Lateral meningocele syndrome 0 trials
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Leptomyelolipoma 0 trials
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Lipomyelomeningocele 0 trials
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Neurenteric cyst 0 trials
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Parietal foramina 0 trials
3 sub-types
- Parietal foramina 1 0 trials
- Parietal foramina 2 0 trials
- Parietal foramina 3 0 trials
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Keyhole surgery in the womb could fix spinal defects with fewer risks
Disease control CompletedThis study tests a new, minimally invasive surgical technique to repair open neural tube defects (spina bifida) in unborn babies. Instead of opening the uterus, surgeons use a tiny camera and tools inserted through small incisions. The goal is to close the spinal defect effective…
Phase 1 • Sponsor: Baylor College of Medicine • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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Does dolutegravir raise the risk of birth defects? eswatini study investigates
Knowledge-focused CompletedResearchers are tracking birth outcomes for infants born in Eswatini to mothers who took dolutegravir or other HIV drugs around the time of conception. The study compares rates of neural tube defects and other birth defects among babies born to HIV-positive women on dolutegravir,…
Sponsor: Elizabeth Glaser Pediatric AIDS Foundation • Aim: Knowledge-focused
Last updated Sep 12, 2026 00:00 UTC