Mucinous adenocarcinoma of the appendix
MONDO:0018330Mucinous adenocarcinoma of the appendix is a very rare, slow growing, well-differentiated epithelial neoplasm of the appendix characterized by abundant mucin production. Clinically, it presents as acute appendicitis (with abdominal pain, fever, leukocytosis) or as pseudomyxoma peritonei (wide-spread presence of mucin within the peritoneal cavity), however some patients may be completely asymptomatic at the time of diagnosis. In many cases, a second gastrointestinal malignancy is present.
Also known as: appendiceal mucinous adenocarcinoma, appendix mucinous adenocarcinoma, vermiform appendix mucinous adenocarcinoma
2913 clinical trials for this condition and its sub-types, 4 tagged with Mucinous adenocarcinoma of the appendix itself.
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Browse by category →Sub-types of Mucinous adenocarcinoma of the appendix
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Pseudomyxoma peritonei 17 trials
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Appendix mucinous cystadenocarcinoma 0 trials
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Immunotherapy duo takes on rare tumors
Disease control OngoingThis phase 2 trial is testing a combination of two immunotherapy drugs, nivolumab and ipilimumab, in 798 people with over 50 types of rare cancers. The goal is to see if these drugs can shrink tumors by helping the immune system attack cancer cells. Participants receive the drugs…
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Doctors question chemo for rare belly cancer: study seeks answers
Knowledge-focused OngoingThis study looks at whether chemotherapy slows tumor growth in people with a rare type of appendiceal cancer that has spread. About 30 participants will be observed with and without chemotherapy to compare tumor growth rates. The goal is to give doctors clearer guidance on whethe…
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Heated chemo during surgery: does it slow down gut recovery?
Knowledge-focused OngoingThis study looks back at 193 people with stomach, appendix, or colon cancer who had surgery with or without heated chemotherapy (HIPEC). Researchers want to see if HIPEC affects how quickly the bowels start working again after surgery and whether it leads to more complications. T…
Sponsor: Peking University People's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC