Monogenic diabetes
MONDO:0015967Diabetes mellitus that is caused by mutations in a single gene.
Also known as: monogenic diabetes, rare genetic diabetes mellitus
57 clinical trials for this condition and its sub-types, 9 tagged with Monogenic diabetes itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Monogenic diabetes
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Maturity-onset diabetes of the young 8 trials · 13 incl. sub-types
15 sub-types
- Maturity-onset diabetes of the young type 2 4 trials
- Maturity-onset diabetes of the young type 1 1 trial
- Maturity-onset diabetes of the young type 4 1 trial
- Fanconi renotubular syndrome 4 with maturity-onset diabetes of the young 0 trials
- Maturity-onset diabetes of the young type 10 0 trials
- Maturity-onset diabetes of the young type 11 0 trials
- Maturity-onset diabetes of the young type 13 0 trials
- Maturity-onset diabetes of the young type 14 0 trials
- Maturity-onset diabetes of the young type 3 0 trials
- Maturity-onset diabetes of the young type 6 0 trials
- Maturity-onset diabetes of the young type 7 0 trials
- Maturity-onset diabetes of the young type 8 0 trials
- Maturity-onset diabetes of the young type 9 0 trials
- Maturity-onset diabetes of the young, type 12 0 trials
- Renal cysts and diabetes syndrome 0 trials
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Neonatal diabetes mellitus 3 trials · 6 incl. sub-types
Most studied deeper sub-types
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New pill could tame rare genetic diabetes
Disease control Recruiting nowThis study tests a new drug called dorzagliatin in 44 adults with a rare, inherited form of diabetes (GCK-MODY). The drug works by activating a key enzyme to help the body better control blood sugar. Participants will receive both the drug and a placebo at different times to see …
Phase 2 • Sponsor: Chinese University of Hong Kong • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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Double transplant aims to cure diabetes in kids with weak immune systems
Disease control Recruiting nowThis study tests a two-step transplant for children with type 1 diabetes who also have an immune deficiency. First, they receive umbilical cord blood stem cells to rebuild their immune system. Then, if that works well, they get a transplant of insulin-producing islet cells. The g…
Sponsor: Children's Hospital of Fudan University • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Massive genetic diabetes hunt launches in china
Knowledge-focused Recruiting nowThis study is creating a large digital registry to find and understand rare forms of diabetes caused by a single gene (monogenic diabetes). Researchers will enroll up to 5,000 people in China who were diagnosed with diabetes at a young age and test their DNA. The goal is to learn…
Sponsor: Tianjin Medical University General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Rare genes reveal secrets of diabetes and insulin disorders
Knowledge-focused Recruiting nowThis study looks at people with rare genetic changes that affect beta cells, which control blood sugar. Researchers will collect blood samples and optional MRI scans to find biomarkers and understand how these genes change body function. No treatment is given, and participants co…
Sponsor: University of Exeter • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC