Melanoma, cutaneous malignant, susceptibility to, 8

An inherited cancer-predisposing syndrome due to a gain-of-function germline mutation in the MITF gene, associated with a higher incidence of amelanotic and nodular melanoma, multiple primary melanomas and increase in nevus number and size. It may also predispose to co-occurring melanoma and renal cell carcinoma and to pancreatic cancer.

Also known as: MITF-related melanoma and renal cell carcinoma predisposition syndrome, melanoma, cutaneous malignant, susceptibility to, 8, melanoma, cutaneous malignant, susceptibility to, type 8, CMM8, melanoma and renal cell carcinoma, susceptibility to, susceptibility to cutaneous malignant melanoma 8

36 clinical trials for this condition and its sub-types.