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Medulloblastoma SHH activated

MONDO:0850197

A medulloblastoma that is characterized as a molecular subtype by activation of the sonic hedgehog (SHH) pathway and TP53 mutations that may be present or absent.

1509 clinical trials for this condition and its sub-types, 3 tagged with Medulloblastoma SHH activated itself.

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↑ Medulloblastoma (111)

Sub-types of Medulloblastoma SHH activated

Medulloblastoma SHH activated and TP53 mutant 1 trial
Medulloblastoma SHH activated and TP53 wild-type 1 trial

Including sub-types (1509) Tagged with Medulloblastoma SHH activated (3)

Trials to join now! 1 Not yet recruiting 1 Terminated 1

Brain tumor trial aims to find kinder chemo for toddlers

Disease control Not yet recruiting

This phase 3 trial compares two standard chemotherapy regimens for children under 5 with a low-risk type of medulloblastoma. The main goal is to see which approach better protects thinking and learning skills 2.5 years after diagnosis. The study will also track survival and side …

Phase 3 • Sponsor: Nationwide Children's Hospital • Aim: Disease control

Last updated Jun 27, 2026 08:05 UTC