Mastocytosis
MONDO:0007950A clonal myeloproliferative neoplasm characterized by the proliferation and accumulation of neoplastic mast cells in one or multiple organs or organ systems. It is a heterogeneous group of neoplasms, ranging from cutaneous proliferations which may regress spontaneously, to aggressive neoplasms associated with organ failure and short survival.
Also known as: Mast cell disease, mastocytosis, MAST cell disease, urticaria pigmentosa
1884 clinical trials for this condition and its sub-types, 15 tagged with Mastocytosis itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Mastocytosis
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Systemic mastocytosis 11 trials · 24 incl. sub-types
5 sub-types
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Cutaneous mastocytosis 1 trial
3 sub-types
- Cutaneous mastocytoma 0 trials Sub-types →
- Diffuse cutaneous mastocytosis 0 trials Sub-types →
- Maculopapular cutaneous mastocytosis 0 trials Sub-types →
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Acute mast cell leukemia 0 trials
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Chronic mast cell leukemia 0 trials
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Mast cell sarcoma 0 trials
Most studied deeper sub-types
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New Two-Step transplant shows promise for blood cancer patients
Disease control CompletedThis study tested a two-step stem cell transplant for people with blood cancers like leukemia and lymphoma. First, patients received low-dose chemotherapy and radiation to prepare their bodies. Then, they got donor stem cells followed by drugs to prevent the donor cells from atta…
Phase 2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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Drug dasatinib tested for rare blood cancers
Disease control CompletedThis study tested the drug dasatinib in 68 adults with several types of blood and bone marrow disorders, including certain leukemias, myelofibrosis, and mastocytosis. The goal was to see if dasatinib could help control the disease and to check its safety. Participants took dasati…
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Blood test norms for kids could end diagnostic delays
Knowledge-focused CompletedThis completed study measured normal tryptase levels in 402 children aged 0-18 to help doctors better diagnose mast cell disorders like mastocytosis and MCAS. Researchers used leftover blood from routine tests in children undergoing surgery. Knowing these normal ranges could redu…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:52 UTC