Long QT syndrome 2
MONDO:0013367An autosomal dominant condition caused by mutation(s) in the KCNH2 gene, encoding potassium voltage-gated channel subfamily H member 2. It is characterized by a prolonged QT interval that may result in torsade de pointes, ventricular fibrillation and/or sudden cardiac death.
Also known as: LQT2, Long QT syndrome, acquired, reduced susceptibility to, long QT syndrome 2, long QT syndrome type 2, long QT syndrome 1/2, digenic, long QT syndrome 2, acquired, susceptibility to, long QT syndrome 2/3, digenic, long QT syndrome 2/5, digenic
3 clinical trials for this condition and its sub-types.
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New drug aims to tame dangerous heart rhythms in genetic disorder
Disease control Recruiting nowThis study tests whether the drug THRV-1268 can safely shorten the heart's electrical recovery time (QT interval) in people with Long QT Syndrome Type 2, a genetic condition that raises the risk of dangerous heart rhythms and sudden cardiac arrest. About 64 participants will take…
Phase: PHASE2, PHASE3 • Sponsor: Thryv Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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Heart condition's hidden toll: new study asks patients about life quality
Knowledge-focused Recruiting nowThis study aims to understand how Long QT Syndrome types 2 and 3 affect the quality of life and daily burden of adults. Researchers will ask up to 200 participants to fill out questionnaires about their physical, emotional, and social well-being. No treatment is given; the goal i…
Sponsor: Thryv Therapeutics, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC