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Lathosterolosis

MONDO:0011816

Lathosterolosis is an extremely rare inborn error of sterol biosynthesis characterized by facial dysmorphism, congenital anomalies (including limb and kidney anomalies), failure to thrive, developmental delay and liver disease.

Also known as: lathosterolosis, sterol C5-desaturase deficiency, Sc5D deficiency

3 clinical trials for this condition and its sub-types.

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Broader categories

Disease (680) Metabolic disease (233) Inherited lipid metabolism disorder (189) Hereditary disease (176) Inborn errors of metabolism (45) Human disease (14) Developmental defect during embryogenesis (8) Cholesterol metabolism disease (3) Cholesterol biosynthetic process disease (2) Disease of genetic or genomic mechanism (2)
Trials to join now! 1 Completed 1 Terminated 1
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  • Rare genetic disorder studied for clues to better care

    Knowledge-focused Completed

    This study looked at Smith-Lemli-Opitz syndrome (SLOS), a rare genetic condition that affects cholesterol production and causes birth defects and intellectual disabilities. Researchers enrolled 130 patients and their mothers to learn more about the disease's progression, genetic …

    Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) • Aim: Knowledge-focused

    Last updated Aug 18, 2026 09:00 UTC

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