Isolated congenital anosmia
MONDO:0007137This syndrome is characterized by total or partial anosmia at birth. So far, 15 patients have been described. The anosmia is caused by a defect in the development of the olfactory bulbs or by replacement of the olfactory epithelium by respiratory epithelium. The mode of transmission appears to be autosomal dominant with incomplete penetrance. Isolated congenital anosmia is found in some parents of individuals with Kallman syndrome.
Also known as: ANIC, anosmia, congenital, anosmia, isolated congenital, congenital anosmia
2 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
-
Electric zaps to the forehead may help restore lost sense of smell
Symptom relief Recruiting nowThis study tests whether combining a mild electrical nerve stimulation on the forehead with standard smell training can improve smell function in adults with smell loss. Participants use a small device at home for 8 weeks while smelling four different odors. Researchers measure c…
Phase: PHASE2 • Sponsor: Medical University of South Carolina • Aim: Symptom relief
Last updated Aug 14, 2026 00:00 UTC
-
Can smell training rewire the brain and immune system?
Knowledge-focused Recruiting nowThis study looks at people with smell loss caused by chronic rhinosinusitis. Participants will undergo a 3-month smell training program. Researchers will measure changes in smell function, mental health, and immune markers in blood and tissue samples. The goal is to understand th…
Phase: NA • Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated Jul 04, 2026 00:00 UTC