Intraepithelial neoplasia
MONDO:0024474A precancerous neoplastic process that affects the squamous, glandular, or transitional cell epithelium without evidence of invasion. According to the degree of nuclear atypia, number of mitotic figures, and presence of architectural distortion, it is classified as low grade (mild dysplasia) or high grade (moderate or severe dysplasia).
Also known as: epithelial dysplasia, intraepithelial neoplasia, intraepithelial neoplasm
1515 clinical trials for this condition and its sub-types, 25 tagged with Intraepithelial neoplasia itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Intraepithelial neoplasia
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Squamous cell intraepithelial neoplasia 26 trials · 43 incl. sub-types
3 sub-types
- Cervical squamous intraepithelial neoplasia 28 trials
- Conjunctival intraepithelial neoplasm 0 trials
- Corneal intraepithelial neoplasm 0 trials
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Prostate intraepithelial neoplasia 2 trials
1 sub-type
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New shot aims to stop breast cancer before it starts
Disease control Not yet recruitingThis early-phase trial tests a drug called CAN1012 in 24 people with pre-cancerous breast conditions (DCIS or LCIS). The drug is injected directly into the lesion to activate the immune system. The main goal is to check safety and ensure the treatment doesn't delay necessary surg…
Phase 1 • Sponsor: Providence Health & Services • Aim: Disease control
Last updated Jul 25, 2026 00:00 UTC
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Genetically modified cells injected into mouth lesions to stop cancer before it starts
Disease control Not yet recruitingThis early-phase trial tests whether specially engineered immune cells (NK cells) can safely treat high-risk precancerous spots in the mouth. The cells are injected directly into the lesions and are designed to target a protein called TROP2, while also resisting signals that norm…
Phase 1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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New shot aims to stop mouth lesions before they become cancer
Disease control Not yet recruitingThis early-phase trial tests a drug called CAN1012, which is injected directly into pre-cancerous mouth lesions. The goal is to see if it is safe and can activate the immune system to fight the abnormal cells. The study involves 36 adults with oral epithelial dysplasia who will r…
Phase 1 • Sponsor: Providence Health & Services • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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Could a simple drug combo speed up stomach ulcer healing after cancer surgery?
Disease control Not yet recruitingThis study looks at whether adding sucralfate (a protective coating agent) to standard esomeprazole (a stomach acid reducer) helps heal artificial ulcers created during endoscopic surgery for early stomach cancer or precancerous growths. About 120 adults will be randomly assigned…
Phase 4 • Sponsor: LanZhou University • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Scientists hunt for biomarkers to catch pancreatic cancer before it strikes
Diagnosis Not yet recruitingThis study aims to find molecular clues that could predict whether certain pancreatic growths will turn into cancer. Researchers will analyze tissue from patients having pancreatic surgery, using advanced genetic and protein tests on both the original tissue and lab-grown 3D cell…
Sponsor: Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis • Aim: Diagnosis
Last updated Jul 18, 2026 00:00 UTC