Intellectual developmental disorder with neuropsychiatric features
MONDO:0044322Intellectual developmental disorder with neuropsychiatric features is an autosomal recessive disorder characterized by moderate intellectual disability, relatively mild seizures, and neuropsychiatric abnormalities, such as anxiety, obsessive-compulsive behavior, and autistic features. Mild facial dysmorphic features may also be present (summary by {2:Srour et al., 2017}).
Also known as: intellectual developmental disorder with neuropsychiatric features, IDDNPF
28 clinical trials for this condition and its sub-types.
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New DNA tests could spot hidden chromosome flaws in infertility and developmental disorders
Diagnosis CompletedThis study tested two new technologies—optical genome mapping and long-read DNA sequencing—against standard chromosome tests in 350 people with infertility, intellectual disability, birth defects, or miscarriage. The goal was to see if these newer methods can find more chromosome…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Diagnosis
Last updated Jun 27, 2026 14:01 UTC
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Can an iPad game spot autism early?
Diagnosis CompletedThis study tested whether an iPad game (Play.Care) could help diagnose autism spectrum disorder (ASD) in children aged 2.5 to 5 years. The game measures how children move while playing, since movement differences may be early signs of autism. Researchers compared the game's resul…
Phase: NA • Sponsor: University of Strathclyde • Aim: Diagnosis
Last updated Jun 27, 2026 12:09 UTC
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New spatula could open mouths for better dental care in disabled patients
Symptom relief CompletedThis study tested a special spatula designed to help dentists examine the teeth of people with mental disabilities who have behavioral issues. The goal was to see if the spatula makes it easier and safer to look inside the mouth. Two hundred participants were included, and the st…
Phase: NA • Sponsor: Centre Hospitalier Régional Metz-Thionville • Aim: Symptom relief
Last updated Jun 27, 2026 14:01 UTC
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Fun card game shows promise for sharper minds in intellectual disability
Symptom relief CompletedThis study tested a new card game called 'Wai Ji Match Fun' designed for adults with mild to moderate intellectual disabilities. 60 participants played the game in weekly group sessions for 8 weeks. Researchers measured how feasible and acceptable the game was, and whether it imp…
Phase: NA • Sponsor: The Hong Kong Polytechnic University • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Parenting classes boost Well-Being for moms and dads of kids with intellectual disabilities
Symptom relief CompletedThis study looked at whether a 5-week parenting training program could improve the quality of life and parenting skills for parents of children with intellectual disabilities. 141 parents from 11 special schools took part, with 71 receiving the training and 70 in a control group.…
Phase: NA • Sponsor: STIKes Satria Bhakti Nganjuk • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC
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New program aims to help siblings of chronically ill children
Symptom relief CompletedThis completed trial tested a 5-session group program for siblings and parents of children with chronic illness. The goal was to improve sibling mental health, family communication, and quality of life. 288 families participated, with some receiving the program immediately and ot…
Phase: NA • Sponsor: University of Oslo • Aim: Symptom relief
Last updated Jun 26, 2026 18:43 UTC
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Could hidden nerve damage explain pain in kids with developmental delays?
Knowledge-focused CompletedThis completed study looked at whether children with neurodevelopmental disorders (like mitochondrial disease, cerebral palsy, or developmental delay) have fewer small nerve fibers in their skin, which could cause pain. Researchers took small skin biopsies from 203 children—some …
Sponsor: Heinrich-Heine University, Duesseldorf • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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New screening tool aims to spot suicide risk in kids with autism
Knowledge-focused CompletedThis study tested a set of questions to better identify suicide risk in young people aged 8–17 with autism or other neurodevelopmental disorders. Researchers asked 278 participants and their parents about thoughts of self-harm and understanding of death. The goal was to create a …
Sponsor: National Institute of Mental Health (NIMH) • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC