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Immunodeficiency 14
MONDO:0014222Also known as: Activated Phosphoinositide 3-Kinase Delta Syndrome (APDS), immunodeficiency 14, immunodeficiency 14A, autosomal dominant, immunodeficiency type 14, Activated PI3K-Delta syndrome, IMD14, p110-Delta-Activating mutation causing senescent T cells, lymphadenopathy, and immunodeficiency
94 clinical trials for this condition and its sub-types.
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Experimental drug shows promise for rare immune disorder, but study cut short
Disease control TerminatedThis study tested the long-term safety and effectiveness of a drug called CDZ173 in people with APDS/PASLI, a rare genetic condition that causes a weak immune system and swollen lymph nodes. The 37 participants had already taken CDZ173 or a similar drug in a previous study. The t…
Phase: PHASE2, PHASE3 • Sponsor: Pharming Technologies B.V. • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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Can extra care after transplant help older patients live better?
Disease control TerminatedThis study tested two extra care programs—supportive palliative care and clinical management of other health issues—for older or frail patients who had a donor stem cell transplant. The goal was to see if these programs could improve quality of life and survival compared to stand…
Phase: PHASE2, PHASE3 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC