Idiopathic steroid-sensitive nephrotic syndrome
MONDO:0019067Steroid-sensitive nephrotic syndrome (SSNS) is a kidney disease defined by selective proteinuria, hypoalbuminaemia and, on renal biopsy, minimal changes without immunoglobulin deposits.
6 clinical trials for this condition and its sub-types.
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New hope for kids with kidney disease: can dupilumab stop relapses?
Disease control Recruiting nowThis study tests if dupilumab, a drug already used for allergies, can help children with severe nephrotic syndrome stay relapse-free longer. About 66 kids aged 6–18 will get either dupilumab or a placebo injection for 6 months, while slowly reducing their steroid dose. The goal i…
Phase: PHASE2 • Sponsor: National University Hospital, Singapore • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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Personalized trial matching could revolutionize kidney disease treatment
Knowledge-focused Recruiting nowThis study helps people with certain kidney diseases (like nephrotic syndrome and FSGS) find clinical trials that match their specific disease profile. Researchers analyze participants' molecular data to recommend targeted therapies in ongoing trials. The goal is to improve treat…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Scientists hunt for hidden antibodies in Kids' kidney disease
Knowledge-focused Recruiting nowThis study is investigating whether certain autoantibodies, especially those targeting a protein called nephrin, play a role in nephrotic syndrome, a kidney condition that causes swelling and protein loss in urine. Researchers will analyze blood and kidney tissue from 50 children…
Phase: NA • Sponsor: Meyer Children's Hospital IRCCS • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC