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Idiopathic multicentric Castleman disease

MONDO:0035838

Also known as: HHV-8-negative multicentric Castleman disease, Human herpesvirus-8-negative multicentric Castleman disease

49 clinical trials for this condition and its sub-types, 3 tagged with Idiopathic multicentric Castleman disease itself.

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Where it sits in the disease tree

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Part of

↑ Castleman disease (18)

Sub-types of Idiopathic multicentric Castleman disease

Castleman-Kojima disease 0 trials

Including sub-types (49) Tagged with Idiopathic multicentric Castleman disease (3)

Trials to join now! 2 Not yet finished but already full! 1

Rapamycin drug tested for rare castleman disease

Disease control Ongoing

This phase 2 study tests the drug sirolimus (rapamycin) in 7 people with idiopathic multicentric Castleman disease who have not improved with standard therapy. The goal is to see if sirolimus can improve symptoms like fatigue, fever, and night sweats, and shrink enlarged lymph no…

Phase 2 • Sponsor: University of Pennsylvania • Aim: Disease control

Last updated Aug 22, 2026 00:00 UTC