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Idiopathic mast cell activation syndrome

MONDO:0100051

Mast cell activation syndrome where neither an allergy or other underlying disease is association, nor KIT-mutated mast cells are detectable.

Also known as: idiopathic MACS

2 clinical trials for this condition and its sub-types.

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Broader categories

Disease (717) Hematologic disorder (172) Immune system disorder (150) Human disease (15) Mast cell activation syndrome (8) Leukocyte disorder (6) Idiopathic disease (1) Disease by body system or component (0) Disease by etiologic mechanism (0)

Trials to join now! 1 Terminated 1

Pain relief drug trial for mast cell syndrome stalls early

Symptom relief Stopped early

This Phase 2 trial tested whether FSD201 tablets could reduce chronic pain in adults with mast cell activation syndrome. The study planned to enroll many participants but was terminated early with only 2 people. No results are available to show if the drug works or is safe.

Phase 2 • Sponsor: Quantum Biopharma • Aim: Symptom relief

Last updated Jun 27, 2026 12:23 UTC