IDH-mutant anaplastic astrocytoma

This early-phase trial tests a new drug called telaglenastat combined with standard radiation and chemotherapy for people with a specific type of brain tumor (IDH-mutated astrocytoma). The goal is to find the safest dose and see if the combination works better than standard treat…

This expanded access program offers vorasidenib, an oral drug, to people aged 12 and older with IDH-mutated glioma who have had surgery. The drug targets specific genetic mutations in tumor cells. The goal is to see if it can help control the disease without immediate need for ra…

This study follows 71 glioma patients before and after radiation therapy to see how their thinking skills change. Researchers use special brain scans (RS-fMRI) to map which brain networks are most harmed by radiation. The goal is to learn which areas to avoid during treatment pla…