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Hyper-IgM syndrome type 5

MONDO:0011971

Any hyper-IgM syndrome in which the cause of the disease is a mutation in the UNG gene.

Also known as: HIGM5, UNG hyper-IgM syndrome, hyper-IgM syndrome 5, hyper-IgM syndrome caused by mutation in UNG, hyper-IgM syndrome due to UNG deficiency, hyper-IgM syndrome due to uracil N-glycosylase, hyper-IgM syndrome type 5, immunodeficiency with hyper IgM, type 5

89 clinical trials for this condition and its sub-types.

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Broader categories

Disease (618) Hereditary disease (172) Hematologic disorder (160) Immune system disorder (140) Inborn error of immunity (113) Immunodeficiency disease (48) Human disease (14) Hyper-IgM syndrome (8) Leukocyte disorder (5) B cell deficiency (4)
Trials to join now! 47 Not yet recruiting 8 Not yet finished but already full! 9 Completed 24 Terminated 1
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  • Can extra care after transplant help older patients live better?

    Disease control Terminated

    This study tested two extra care programs—supportive palliative care and clinical management of other health issues—for older or frail patients who had a donor stem cell transplant. The goal was to see if these programs could improve quality of life and survival compared to stand…

    Phase: PHASE2, PHASE3 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control

    Last updated Jun 27, 2026 08:10 UTC

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