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Hydronephrosis

MONDO:0005510

Collection of urine in the renal pelvis that results in dilatation of the renal pelvis and calyces. It is caused by obstruction of urine flow, nephrolithiasis, or vesicoureteral reflux. Signs and symptoms include flank pain, nausea, vomiting, fever, and dysuria.

9 clinical trials for this condition and its sub-types, 7 tagged with Hydronephrosis itself.

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Where it sits in the disease tree

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Part of

↑ Kidney disorder (4039) ↑ Urinary tract obstruction (27)

Sub-types of Hydronephrosis

Congenital hydronephrosis 3 trials

Including sub-types (9) Tagged with Hydronephrosis (7)

Trials to join now! 4 Not yet recruiting 1 Not yet finished but already full! 1 Completed 1

Immunotherapy combo shows promise for bladder cancer patients unable to get chemo

Disease control Ongoing

This early-phase trial is testing whether giving two immunotherapy drugs (durvalumab and tremelimumab) before surgery can help patients with aggressive bladder cancer who cannot take standard chemotherapy. The study involves 54 participants and primarily looks at safety and how t…

Early phase 1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control

Last updated Sep 16, 2026 00:00 UTC