Hydrocephalus

This study looks at 100 Ugandan infants under 6 months old with hydrocephalus caused by a brain infection. It compares two surgeries: a standard shunt and a newer procedure called ETV/CPC. The goal is to see which treatment leads to better brain growth and thinking skills over tw…

This study tests a surgery called ETV/CPC as an alternative to standard shunts for infants with hydrocephalus in Uganda. Shunts often fail and need lifelong maintenance, but ETV/CPC aims to give babies a shunt-free life. Researchers will follow 400 infants to see how well the sur…

This pilot study tests a new device called the eShunt, which is placed in a blood vessel to drain extra fluid from the brain in people with normal pressure hydrocephalus (NPH). NPH causes trouble walking, thinking, and bladder control. The device aims to be a less invasive altern…

This study tests a new device called the eShunt System for people with communicating hydrocephalus, a condition where excess fluid builds up in the brain. The device is a small, permanent implant placed through a blood vessel to drain the extra fluid, avoiding the need for tradit…

This study follows 160 people who have or will get a CODMAN CERTAS Plus valve, a device implanted in the brain to drain extra fluid. The main goal is to see if the valve is placed correctly and works without problems 30 days after surgery. Participants include children and adults…

This study tests a new wireless sensor placed in the brain during shunt surgery for hydrocephalus. The sensor aims to let patients and caregivers monitor brain pressure from home, reducing the need for hospital scans and easing fear of shunt blockages. It is a first-in-human safe…

This trial tests whether magnetic resonance elastography (MRE), a special MRI that measures tissue stiffness, can distinguish normal pressure hydrocephalus from brain atrophy. Current scans often cannot tell the two apart, leading to missed or delayed diagnosis. Researchers will …

This study tests a modified soft contact lens to measure pressure inside the skulls of babies at risk for hydrocephalus (fluid buildup in the brain). About 25 infants will wear the lens during standard checkups and before/after surgery. The goal is to see if the lens can accurate…

This study is observing 328 adults who receive a Neuro-Patch during brain or spine surgery to repair the protective lining around the brain or spinal cord. Researchers are tracking complications and how easy the patch is for surgeons to use. The goal is to gather real-world data …