Hormone-resistant breast carcinoma
MONDO:0056813Breast carcinoma that does not respond to hormone therapy.
Also known as: hormone-refractory breast cancer, hormone-resistant breast cancer, hormone-resistant breast carcinoma
2809 clinical trials for this condition and its sub-types, 5 tagged with Hormone-resistant breast carcinoma itself.
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New hope for Hard-to-Treat breast cancer? alisertib combo tested
Disease control CompletedThis phase II trial tested the drug alisertib, alone or combined with fulvestrant, in 96 postmenopausal women with advanced breast cancer that no longer responds to hormone therapy. Alisertib blocks enzymes that help cancer cells grow, while fulvestrant blocks estrogen. The goal …
Phase 2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Sep 03, 2026 00:00 UTC
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Math models may tame chemo side effects in breast cancer
Disease control CompletedThis early-phase trial tested whether using mathematical models to schedule chemotherapy drugs docetaxel and epirubicin could reduce severe side effects in 17 patients with metastatic breast cancer. The goal was to find the safest dose and schedule while still giving six cycles o…
Phase 1 • Sponsor: Hospices Civils de Lyon • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC