Herpes simplex type 1 infectious disease
MONDO:0100359A disease caused by infection with herpes simplex type 1.
7 clinical trials for this condition and its sub-types, 4 tagged with Herpes simplex type 1 infectious disease itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Herpes simplex type 1 infectious disease
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Experimental herpes vaccine passes first safety check in small trial
Vaccine CompletedThis early-stage trial tested whether a new herpes vaccine called HSV529 is safe for people. Researchers gave the vaccine or a placebo to 69 healthy adults aged 18 to 40, some of whom had herpes and some who did not. Participants received three shots over six months and were moni…
Phase 1 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Vaccine
Last updated Sep 03, 2026 00:00 UTC
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Could a common cold sore drug slow Alzheimer's?
Disease control CompletedThis study tested whether the antiviral drug valacyclovir (Valtrex) could slow brain changes linked to Alzheimer's in 50 people with mild cognitive impairment who also had herpes simplex virus antibodies. Participants took either valacyclovir or a placebo for 52 weeks. The goal w…
Phase 2 • Sponsor: New York State Psychiatric Institute • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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Could a common cold sore drug slow Alzheimer's? new study explores the link.
Disease control CompletedThis study tested whether the antiviral drug valacyclovir (Valtrex) can slow memory loss in people with mild Alzheimer's disease who also carry the herpes simplex virus. About 120 participants received either the drug or a placebo for 18 months. The goal was to see if treating th…
Phase 2 • Sponsor: Columbia University • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC