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Hereditary spastic paraplegia 17

MONDO:0010043

Any hereditary spastic paraplegia in which the cause of the disease is a mutation in the BSCL2 gene.

Also known as: BSCL2 hereditary spastic paraplegia, SPG17, Silver spastic paraplegia syndrome, Silver syndrome, autosomal dominant spastic paraplegia type 17, hereditary spastic paraplegia caused by mutation in BSCL2, hereditary spastic paraplegia type 17, spastic paraplegia with amyotrophy of hands and feet

15 clinical trials for this condition and its sub-types.

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Broader categories

Disease (680) Nervous system disorder (231) Hereditary disease (176) Neurodegenerative disease (171) Peripheral nervous system disorder (114) Central nervous system disorder (107) Neuromuscular disease (106) Spinal muscular atrophy (100) Peripheral neuropathy (91) Motor neuron disorder (62)
Trials to join now! 12 Not yet finished but already full! 1 Completed 1 Terminated 1
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  • Laser test could objectively measure nerve pain for first time

    Diagnosis Completed

    This study tested whether a diode laser can act as a biomarker to measure neuropathic pain in people with peripheral neuropathy. Researchers compared pain responses to a lidocaine patch versus a placebo patch in 75 participants. The goal was to see if the laser test could disting…

    Phase: NA • Sponsor: University of Utah • Aim: Diagnosis

    Last updated Jun 27, 2026 12:09 UTC

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