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Hereditary breast ovarian cancer syndrome

MONDO:0003582

An autosomal dominant inherited syndrome caused by mutations in the BRCA1 or BRCA2 genes. Patients are at high risk of developing breast cancer, particularly before the age of fifty, high risk of developing a second primary breast cancer, and high risk of developing both breast and ovarian cancer.

Also known as: BRCA1- and BRCA2-associated hereditary breast and ovarian cancer (HBOC), Hereditary Breast and Ovarian Cancer Syndrome, familial breast and ovarian cancer syndrome, familial breast/ovarian cancer (BRCA1, BRCA2), hereditary breast and ovarian cancer, hereditary breast and ovarian cancer syndrome, hereditary breast ovarian cancer syndrome, hereditary breast/ovarian cancer (BRCA1, BRCA2)

65 clinical trials for this condition and its sub-types.

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Sub-types

Breast-ovarian cancer, familial, susceptibility to, 1 (3) Breast-ovarian cancer, familial, susceptibility to, 2 (2)

Broader categories

Disease (618) Hereditary disease (172) Inherited disease susceptibility (69) Hereditary neoplastic syndrome (57) Syndromic disease (24) Human disease (14) Neoplastic disease or syndrome (6) Disease susceptibility (3) Disease of genetic or genomic mechanism (2) Autosomal dominant disease (0)
Trials to join now! 27 Not yet recruiting 6 Not yet finished but already full! 19 Completed 13
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