Hemorrhagic disease
MONDO:0002243Spontaneous or near spontaneous bleeding caused by a defect in clotting mechanisms (blood coagulation disorders) or another abnormality causing a structural flaw in the blood vessels (hemostatic disorders).
Also known as: bleeding diathesis, bleeding disorder, bleeding predisposition, bleeding tendency
510 clinical trials for this condition and its sub-types, 108 tagged with Hemorrhagic disease itself.
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Sub-types of Hemorrhagic disease
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Hemophilia A 180 trials
5 sub-types
- Severe hemophilia A 50 trials
- Moderately severe hemophilia A 4 trials
- Mild hemophilia A 2 trials
- Hemophilia A with vascular abnormality 0 trials
- Symptomatic form of hemophilia A in female carriers 0 trials
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Purpura 4 trials · 117 incl. sub-types
3 sub-types
- Thrombocytopenic purpura 8 trials · 116 incl. sub-types Sub-types →
- Hyperglobulinemic purpura 0 trials
- Purpura fulminans 0 trials Sub-types →
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Hemophilia B 84 trials · 91 incl. sub-types
4 sub-types
- Severe hemophilia B 9 trials
- Moderately severe hemophilia B 2 trials
- Mild hemophilia B 1 trial
- Symptomatic form of hemophilia B in female carriers 0 trials
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Vascular hemostatic disease 62 trials · 63 incl. sub-types
2 sub-types
- Cavernous hemangioma 1 trial Sub-types →
- Shwartzman phenomenon 0 trials
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Hereditary von Willebrand disease 18 trials · 29 incl. sub-types
5 sub-types
- Von Willebrand disease 3 9 trials
- Von Willebrand disease 2 4 trials · 5 incl. sub-types Sub-types →
- Von Willebrand disease 1 3 trials
- Von Willebrand disease, X-linked form 0 trials
- Platelet-type von Willebrand disease 0 trials
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Inherited bleeding disorder, platelet-type 6 trials · 26 incl. sub-types
28 sub-types
- Glanzmann thrombasthenia 8 trials Sub-types →
- Platelet-type bleeding disorder 10 8 trials
- Congenital thrombotic thrombocytopenic purpura 5 trials
- Macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss 1 trial
- Bernard-Soulier syndrome 0 trials Sub-types →
- Ehlers-Danlos syndrome, fibronectinemic type 0 trials
- Quebec platelet disorder 0 trials
- Scott syndrome 0 trials
- Bleeding diathesis due to thromboxane synthesis deficiency 0 trials
- Bleeding disorder, platelet-type, 21 0 trials
- Bleeding disorder, platelet-type, 22 0 trials
- Bleeding disorder, platelet-type, 24 0 trials
- Bleeding disorder, platelet-type, 25 0 trials
- Cytosolic phospholipase-A2 alpha deficiency associated bleeding disorder 0 trials
- Gray platelet syndrome 0 trials
- Platelet-type bleeding disorder 11 0 trials
- Platelet-type bleeding disorder 12 0 trials
- Platelet-type bleeding disorder 14 0 trials
- Platelet-type bleeding disorder 15 0 trials
- Platelet-type bleeding disorder 16 0 trials
- Platelet-type bleeding disorder 17 0 trials
- Platelet-type bleeding disorder 18 0 trials
- Platelet-type bleeding disorder 19 0 trials
- Platelet-type bleeding disorder 20 0 trials
- Platelet-type bleeding disorder 8 0 trials
- Platelet-type bleeding disorder 9 0 trials
- Platelet-type von Willebrand disease 0 trials
- Primary release disorder of platelets 0 trials
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Acquired hemophilia 2 trials · 8 incl. sub-types
3 sub-types
- Acquired hemophilia A 6 trials
- Acquired factor XI deficiency 0 trials
- Acquired hemophilia B 0 trials
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Factor VII deficiency 6 trials
2 sub-types
- Congenital factor VII deficiency 3 trials
- Acquired factor VII deficiency 0 trials
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Congenital fibrinogen deficiency 2 trials · 6 incl. sub-types
1 sub-type
- Familial dysfibrinogenemia 2 trials · 6 incl. sub-types Sub-types →
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3 sub-types
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Congenital vitamin K-dependent coagulation factors deficiency 0 trials · 4 incl. sub-types
5 sub-types
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Acquired von willebrand syndrome 3 trials
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Factor X deficiency 2 trials
2 sub-types
- Acquired factor X deficiency 1 trial
- Congenital factor X deficiency 0 trials
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Congenital factor XII deficiency 1 trial
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East Texas bleeding disorder 0 trials
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Alpha-2-plasmin inhibitor deficiency 0 trials
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Congenital factor V deficiency 0 trials
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Congenital factor XI deficiency 0 trials
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Congenital factor XIII deficiency 0 trials
2 sub-types
- Factor XIII, A subunit, deficiency of 0 trials
- Factor XIII, b subunit, deficiency of 0 trials
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Hemophilia B leyden 0 trials
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Inherited prekallikrein deficiency 0 trials
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Prothrombin deficiency 0 trials
2 sub-types
- Acquired prothrombin deficiency 0 trials
- Congenital prothrombin deficiency 0 trials
Most studied deeper sub-types
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Aspirin study for kidney patients halted early – did the risks outweigh the benefits?
Disease control Stopped earlyThis study looked at whether taking a daily low-dose aspirin could help people with chronic kidney disease avoid their first heart attack or stroke. Over 4,600 participants were randomly assigned to take aspirin or receive usual care. The trial was stopped early, and the final re…
Phase 3 • Sponsor: University of Southampton • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Bleeding breakthrough fizzles: fibrinogen trial for chemo patients halted after just one patient
Disease control Stopped earlyThis study tested a single injection of fibrinogen concentrate followed by a platelet transfusion in blood cancer patients with severe bleeding who did not respond to standard platelet transfusions. The goal was to see if it improved blood clotting. However, the trial was termina…
Phase 2 • Sponsor: Centre Hospitalier Universitaire de Saint Etienne • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC