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Growth hormone insensitivity with immune dysregulation 1, autosomal recessive

MONDO:0100211

Also known as: Laron syndrome due to postreceptor defect, Laron syndrome with immunodeficiency, Laron-like syndrome, growth hormone insensitivity due to postreceptor defect, short stature due to STAT5b deficiency, growth hormone insensitivity with immunodeficiency

13 clinical trials for this condition and its sub-types.

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Broader categories

Disease (618) Hereditary disease (172) Immune system disorder (140) Endocrine system disorder (61) Syndromic disease (24) Hereditary endocrine growth disease (23) Human disease (14) Autosomal recessive disease (4) Disease of genetic or genomic mechanism (2) Autosomal genetic disease (0)
Trials to join now! 8 Not yet recruiting 1 Not yet finished but already full! 1 Completed 3
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  • New hope for rare immune disorders: upadacitinib trial launches

    Disease control Not yet recruiting

    This study tests the drug upadacitinib (Rinvoq) in 30 people with rare genetic disorders that overactivate the JAK-STAT immune pathway. The trial has four phases over 12 months, including an open-label phase to find the best dose and a randomized withdrawal phase to compare the d…

    Phase: PHASE1, PHASE2 • Sponsor: Lisa Satter • Aim: Disease control

    Last updated Jul 04, 2026 00:00 UTC

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