GBA1-related Parkinson disease, susceptibility
MONDO:1040030A susceptibility or predisposition to Parkinsons disease in which the cause of the disease is the presence of a monoallelic pathogenic variant or risk allele in the GBA1 gene.
6 clinical trials for this condition and its sub-types, 6 tagged with GBA1-related Parkinson disease, susceptibility itself.
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Gene therapy injection targets Parkinson's in patients with GBA1 mutations
Disease control Not yet recruitingThis early-phase trial tests a gene therapy called VGN-R08b in 17 people with Parkinson's disease who have a GBA1 gene mutation. The therapy is injected directly into the brain's fluid spaces to try to improve symptoms. The main goals are to check safety and see if it works.
Phase 1/2 • Sponsor: Shanghai Vitalgen BioPharma Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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New study aims to unravel Parkinson's protein mysteries
Knowledge-focused Not yet recruitingThis study looks at how abnormal proteins, like alpha-synuclein and tau, build up and affect brain function in people with Parkinson's disease. Researchers will use brain scans, blood tests, and skin biopsies to track these changes. The goal is to find better ways to diagnose and…
Sponsor: University of Pavia • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC