Fibrolamellar hepatocellular carcinoma
MONDO:0006210A distinctive type of liver cell carcinoma that arises in non-cirrhotic livers and is seen predominantly in young patients. The tumor cells are polygonal and deeply eosinophilic, and are embedded in a fibrous stroma. The prognosis is similar to classical hepatocellular carcinoma that arises in non-cirrhotic livers, and better than hepatocellular carcinoma that arises in cirrhotic livers.
Also known as: FHCC, FLC, fibrolamellar cancer, fibrolamellar carcinoma, fibrolamellar carcinoma of liver cells, fibrolamellar carcinoma of the liver cells, fibrolamellar hepatocarcinoma, fibrolamellar hepatocellular carcinoma
2924 clinical trials for this condition and its sub-types, 15 tagged with Fibrolamellar hepatocellular carcinoma itself.
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Browse by category →Sub-types of Fibrolamellar hepatocellular carcinoma
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New drug cocktail shows promise in Hard-to-Treat cancers
Disease control CompletedThis early-phase trial tested two drugs—sapanisertib and ziv-aflibercept—in 83 people with advanced solid tumors that had spread or could not be removed. The goal was to find the safest dose and check for side effects. Sapanisertib blocks enzymes that help cancer cells grow, whil…
Phase 1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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New registry aims to unlock secrets of rare liver cancer
Knowledge-focused CompletedThis study gathered information from 12 people with fibrolamellar cancer (FLC) around the world. Participants shared their medical history and regular care details through an online registry. The goal was to create a database for future research, not to provide treatment.
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC