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Fetal and neonatal alloimmune thrombocytopenia

MONDO:0019415

A rare hematological disease characterized by maternal alloimmunisation against fetal platelet antigens that are inherited from the father and different from those present in the mother, and usually presents as a severe isolated thrombocytopenia in otherwise healthy newborns.

Also known as: NAIT

11 clinical trials for this condition and its sub-types.

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Sub-types

Fetomaternal alloimmune thrombocytopenia 1 (0) Fetomaternal alloimmune thrombocytopenia 2 (0) Fetomaternal alloimmune thrombocytopenia 3 (0)

Broader categories

Disease (680) Hereditary disease (176) Hematologic disorder (170) Hemorrhagic disease (103) Human disease (14) Disease of genetic or genomic mechanism (2) Disease by body system or component (0) Disease by etiologic mechanism (0)

Trials to join now! 8 Completed 2 Terminated 1

Promising FNAIT prevention study halted early after just one participant

Prevention Terminated

This study tested a drug called RLYB212 in pregnant women at high risk for a condition where the mother's immune system attacks the baby's platelets, causing dangerous bleeding. The goal was to see if the drug was safe and how it moved through the body. Only one woman enrolled be…

Phase: PHASE2 • Sponsor: Rallybio • Aim: Prevention

Last updated Jun 27, 2026 09:11 UTC