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FAS-related autoimmune lymphoproliferative syndrome

MONDO:1060194

An autoimmune lymphoproliferative syndrome that results from defective lymphocyte homoestasis, and is caused by variants in the FAS gene. It is characterized by non-malignant lymphoproliferation, autoimmune disease, and lifelong increased risk for both Hodgkin and non-Hodgkin lymphoma.

Also known as: FAS-related autoimmune lymphoproliferative syndrome

85 clinical trials for this condition and its sub-types.

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Broader categories

Disease (618) Autoimmune disease (283) Hereditary disease (172) Immune system disorder (140) Inborn error of immunity (113) Lymphoproliferative syndrome (68) Hypersensitivity reaction disease (29) Syndromic disease (24) Human disease (14) Autoimmune lymphoproliferative syndrome (11)

Trials to join now! 39 Not yet recruiting 11 Not yet finished but already full! 13 Completed 21 Terminated 1

Biopsy tolerance study ends early – what we know

Knowledge-focused Terminated

This study aimed to understand how well patients tolerate biopsies for autoimmune diseases and whether they feel properly informed. It planned to enroll 505 people but was terminated early. The results may help improve patient experience with these common procedures.

Sponsor: University Hospital, Brest • Aim: Knowledge-focused

Last updated Jun 28, 2026 00:00 UTC