Familial juvenile hypertrophy of the breast
MONDO:0007237Familial juvenile hypertrophy of the breast is a rare breast malformation disorder characterized by unilateral or bilateral, symmetrical or asymmetrical, uncontrolled, rapid and massive enlargement of the breast(s) in peripubertal females, occurring in various members of a family. Additional associated manifestations may include skin hyperemia, dilated subcutaneous veins, skin necrosis, kyphosis, lordosis and anonychia. Growth and development are otherwise normal.
Also known as: familial juvenile gigantomastia, juvenile gigantomastia, juvenile macromastia, virginal breast hypertrophy, virginal mammary hypertrophy, JHB, gigantomastia, juvenile, hypertrophy of the breast, juvenile
7 clinical trials for this condition and its sub-types.
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New study aims to cut narcotic use in breast reduction surgery
Symptom relief Recruiting nowThis study looks at whether a special nerve block given during breast reduction surgery can control pain as well as standard narcotic painkillers, but without the side effects. About 80 women having breast reduction will be split into two groups: one gets the nerve block plus non…
Phase: PHASE4 • Sponsor: Carilion Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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New wound dressing could speed healing after breast reduction
Symptom relief Recruiting nowThis study tests whether a closed incision negative pressure wound therapy (ciNPWT) device can reduce wound complications after breast reduction surgery. 92 women will have one breast treated with the device and the other with standard adhesive strips. The goal is to see if the d…
Phase: NA • Sponsor: Medstar Health Research Institute • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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AI takes on breast cancer detection: can machines match expert radiologists?
Knowledge-focused Recruiting nowThis study will test how well artificial intelligence (AI) can interpret breast ultrasound images using the latest BI-RADS criteria. Researchers will collect over 1,300 past ultrasound images with confirmed diagnoses and have expert radiologists annotate them. Then, various AI mo…
Sponsor: Peking Union Medical College Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC