Familial episodic pain syndrome with predominantly lower limb involvement
MONDO:0014247A rare, autosomal dominant disorder caused by mutation in the SCN11A gene. It is characterized by intense episodic pain mainly affecting the distal lower extremities in early childhood. The pain diminishes with age.
Also known as: episodic pain syndrome, familial, type 3, FEPS3, episodic pain syndrome, familial, 3
11 clinical trials for this condition and its sub-types.
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Gene therapy readiness check: new study maps virus immunity in muscle disease patients
Knowledge-focused Not yet recruitingThis study will test blood samples from 450 people aged 6 to 60 with inherited neuromuscular diseases to see if they have antibodies that could block gene therapy viruses (AAVs). The goal is to understand how common these antibodies are and which patients might be good candidates…
Phase: NA • Sponsor: Genethon • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Global database launched to see if nerve-zapping devices really work
Knowledge-focused Not yet recruitingThis study creates a large international database to monitor how well spinal cord stimulation and similar nerve therapies work for people with chronic nerve pain. Researchers will collect real-world data from 1,000 patients across multiple countries to track safety, quality of li…
Sponsor: Poitiers University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC