External ear disorder

This phase 2 trial is testing whether giving the immunotherapy drug tislelizumab along with chemotherapy before surgery can shrink advanced squamous cell carcinoma of the ear canal. The goal is to make surgery easier and safer, especially to protect important nerves near the ear.…

This study compares black seed (Nigella sativa) oil to standard steroid ear drops for treating eczema in the ear canal. 85 adults with ear eczema will use either the oil or steroid drops twice daily for 10 days. Researchers will measure changes in inflammation, itching, and pain …

This study tests whether a 20-minute session of passive music therapy, delivered through an app just before entering the operating room, can lower anxiety and pain in adults undergoing ear, nose, or throat surgery. Five hundred participants will be randomly assigned to receive mu…

This study will collect ear swabs from 40 people with malignant otitis externa, a severe infection of the ear canal that mainly affects people with diabetes or weakened immune systems. Researchers will culture the samples to identify the bacteria and fungi causing the infection a…