Endemic typhus
MONDO:0000330A bacterial infection caused by Rickettsia typhi.
Also known as: endemic flea-borne typhus, endemic typhus fever, murine typhus, urban typhus
10 clinical trials for this condition and its sub-types, 1 tagged with Endemic typhus itself.
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New antibiotic cocktail aimed at Drug-Resistant infections in babies
Disease control Recruiting nowThis study tests a combination of two antibiotics, aztreonam and avibactam, in newborns and infants up to 9 months old who have serious infections caused by gram-negative bacteria. The trial has two parts: one to see how a single dose moves through the body, and another to test m…
Phase 2 • Sponsor: Pfizer • Aim: Disease control
Last updated Oct 17, 2026 00:00 UTC
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Typhus treatment Face-Off: which antibiotic clears bacteria faster?
Disease control Recruiting nowMurine and scrub typhus are bacterial infections spread by fleas and mites. Doctors often treat them with doxycycline or azithromycin, but they do not know which drug clears the bacteria faster or how the drugs move through the body. This trial enrolls 72 adults with typhus in La…
Phase 2/3 • Sponsor: Lao-Oxford-Mahosot Hospital Wellcome Trust Research Unit • Aim: Disease control
Last updated Oct 15, 2026 00:00 UTC
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Double antibiotic attack: could a Two-Drug combo beat severe infections faster?
Disease control Recruiting nowThis study tests whether adding a second antibiotic (fosfomycin) to the standard antibiotic (ceftazidime) helps people with severe gram-negative infections recover faster. About 100 hospitalized adults will be randomly assigned to get either the combo or the standard drug plus a …
Phase 3 • Sponsor: Angela HUTTNER • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Real-World watch: is zavicefta safe for tough infections?
Knowledge-focused Recruiting nowThis study observes 600 patients in Korea who receive Zavicefta for complicated abdominal or urinary tract infections or hospital-acquired pneumonia. Researchers track side effects and how well the drug works. It is required by Korean regulators to ensure the drug's safety after …
Sponsor: Pfizer • Aim: Knowledge-focused
Last updated Sep 10, 2026 00:00 UTC
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Scientists hunt Tick-Borne germs to unlock disease patterns
Knowledge-focused Recruiting nowThis study is observing up to 2,000 people in Russia who have or may have rickettsiosis, a tick-borne illness. Researchers will collect leftover blood or swab samples from standard tests to identify the specific germ causing the infection. They will then compare the germ type wit…
Sponsor: Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC