Distal renal tubular acidosis
MONDO:0015827A kidney disorder of impaired net acid secretion by the distal tubule characterized by hyperchloremic metabolic acidosis. Primary distal renal tubular acidosis is often associated with hypokalemia whereas acquired form may be associated with hypokalemia, hyperkalemia or normokalemia.
Also known as: Primary Distal Renal Tubular Acidosis, classic RTA, dRTA, distal renal tubular acidosis (disease), familial distal primary acidosis, renal tubular acidosis type 1, renal tubular acidosis, distal
14 clinical trials for this condition and its sub-types.
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Broader categories
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Can a common supplement shield dialysis Kids' hearts?
Disease control ENROLLING_BY_INVITATIONThis study tests whether a daily dose of alpha lipoic acid, an antioxidant supplement, can lower the risk of heart problems in 50 children who are on regular hemodialysis. Participants will either take the supplement or a placebo pill for a period, and researchers will monitor fo…
Phase: PHASE3 • Sponsor: Ain Shams University • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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Kidney acidosis drug study pulled before it began
Disease control TerminatedThis study was designed to check the long-term safety and effectiveness of a drug called ADV7103 in people with primary distal renal tubular acidosis, a rare kidney problem that leads to too much acid in the blood. It planned to include people who had been in an earlier study, as…
Phase: PHASE3 • Sponsor: Advicenne Pharma • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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Could a diabetes drug shield Kids' kidneys?
Disease control OngoingThis study tests whether dapagliflozin, a drug used in adults for diabetes and kidney protection, can reduce protein leakage in the urine of children with chronic kidney disease. Ten children aged 4 to 18 with persistent proteinuria despite standard therapy will take the drug, an…
Phase: NA • Sponsor: Al-Quds University • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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300 volunteers help create medical image bank for science
Knowledge-focused OngoingThis study gathers MRI, CT, and ultrasound images from 300 adults—some healthy, some with kidney or brain disease—to build a collection for future not-for-profit research. No new treatments are being tested; the goal is to make medical images available to scientists for advancing…
Sponsor: Mario Negri Institute for Pharmacological Research • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:28 UTC