Differentiated thyroid carcinoma
MONDO:0015447Differentiated thyroid carcinoma (DTC), also known as papillary or follicular thyroid carcinoma, is a slow-growing malignancy usually presenting in adults as an asymptomatic thyroid mass.
Also known as: differentiated thyroid cancer, differentiated thyroid carcinoma, differentiated thyroid gland cancer, differentiated thyroid gland carcinoma, papillary or follicular thyroid carcinoma, thyroid gland differentiated carcinoma, thyroid gland well differentiated carcinoma, well differentiated thyroid carcinoma
2927 clinical trials for this condition and its sub-types, 79 tagged with Differentiated thyroid carcinoma itself.
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Sub-types of Differentiated thyroid carcinoma
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Thyroid gland follicular carcinoma 20 trials · 77 incl. sub-types
7 sub-types
- Medullary thyroid gland carcinoma 42 trials · 53 incl. sub-types Sub-types →
- Thyroid Hurthle cell carcinoma 11 trials
- Thyroid cancer, nonmedullary, 2 4 trials
- Thyroid cancer, nonmedullary, 4 0 trials
- Thyroid cancer, nonmedullary, 5 0 trials
- Thyroid gland papillary and follicular carcinoma 0 trials
- Trabecular follicular adenocarcinoma 0 trials
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Thyroid gland papillary carcinoma 59 trials · 60 incl. sub-types
6 sub-types
- Tall cell variant thyroid gland papillary carcinoma 2 trials
- Thyroid cancer, nonmedullary, 1 1 trial
- Columnar cell variant thyroid gland papillary carcinoma 0 trials
- Multicentric papillary thyroid carcinoma 0 trials
- Thyroid gland diffuse sclerosing papillary carcinoma 0 trials
- Thyroid gland papillary and follicular carcinoma 0 trials
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Familial papillary or follicular thyroid carcinoma 1 trial · 13 incl. sub-types
6 sub-types
- Papillary thyroid Microcarcinoma 8 trials
- Thyroid cancer, nonmedullary, 2 4 trials
- Thyroid cancer, nonmedullary, 3 0 trials
- Thyroid cancer, nonmedullary, 4 0 trials
- Thyroid cancer, nonmedullary, 5 0 trials
- Thyroid carcinoma, nonmedullary, with or without cell oxyphilia 0 trials
Most studied deeper sub-types
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Immunotherapy combo tested for tough thyroid cancers
Disease control Stopped earlyThis phase II trial tested two immunotherapy drugs, durvalumab and tremelimumab, in 79 patients with advanced thyroid cancer that had progressed despite treatment. The goal was to see if the combination could slow or stop cancer growth. The study was terminated early, so the full…
Phase 2 • Sponsor: Grupo Espanol de Tumores Neuroendocrinos • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Diabetes drug may ease thyroid treatment side effects
Symptom relief Stopped earlyThis small pilot study tested whether metformin, a common diabetes drug, could reduce side effects like dry mouth and taste changes from radioactive iodine treatment in people with thyroid cancer. Only 13 people took part, and the study was stopped early. The goal was to see if m…
Phase 2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Hunt for hidden thyroid cancer genes ends early
Knowledge-focused Stopped earlyThis study looked for new genes that might increase the risk of developing differentiated thyroid cancer. Researchers planned to analyze the complete DNA of people with thyroid cancer and their family members. The study was stopped early and involved 34 participants.
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC