Craniosynostosis

MONDO:0015469

Craniosynostosis is defined as the premature fusion of one or more cranial sutures leading to secondary distortion of skull shape resulting in skull deformities with a variable presentation. Craniosynostosis may occur in an isolated setting or as part of a syndrome.

Also known as: craniosynostosis syndrome, premature closure of cranial sutures, CSO

39 clinical trials for this condition and its sub-types, 17 tagged with Craniosynostosis itself.

Follow this condition to get notified about new trials

Where it sits in the disease tree

Browse by category →

Part of

↑ Hereditary disease (18235) ↑ Synostosis (40)

Sub-types of Craniosynostosis

Syndromic craniosynostosis 1 trial · 22 incl. sub-types
40 sub-types
- Acrocephalosyndactyly 0 trials · 13 incl. sub-types Sub-types →
- Crouzon syndrome-acanthosis nigricans syndrome 4 trials
- Antley-Bixler syndrome 2 trials Sub-types →
- Muenke syndrome 2 trials
- Crouzon syndrome 1 trial Sub-types →
- Shprintzen-Goldberg syndrome 1 trial
- Pseudoaminopterin syndrome 1 trial
- Baller-Gerold syndrome 0 trials
- Beare-Stevenson cutis gyrata syndrome 0 trials
- C syndrome 0 trials
- Curry-Jones syndrome 0 trials
- Hunter-McAlpine craniosynostosis 0 trials
- Lowry-MacLean syndrome 0 trials
- Summitt syndrome 0 trials
- TCF12-related craniosynostosis 0 trials
- Weiss-Kruszka syndrome 0 trials
- X-linked intellectual disability-plagiocephaly syndrome 0 trials
- Acrocephalopolydactyly 0 trials
- Autosomal dominant intellectual disability-craniofacial anomalies-cardiac defects syndrome 0 trials
- Cardiocranial syndrome, Pfeiffer type 0 trials
- Cloverleaf skull-asphyxiating thoracic dysplasia syndrome 0 trials
- Cloverleaf skull-multiple congenital anomalies syndrome 0 trials
- Cranioectodermal dysplasia 0 trials Sub-types →
- Craniomicromelic syndrome 0 trials
- Craniosynostosis 2 0 trials
- Craniosynostosis 4 0 trials
- Craniosynostosis and dental anomalies 0 trials
- Craniosynostosis, Herrmann-Opitz type 0 trials
- Craniosynostosis, Philadelphia type 0 trials
- Craniosynostosis-anal anomalies-porokeratosis syndrome 0 trials
- Craniosynostosis-cataract syndrome 0 trials
- Craniosynostosis-fibular aplasia syndrome 0 trials
- Craniosynostosis-hydrocephalus-Arnold-Chiari malformation type I-radioulnar synostosis syndrome 0 trials
- Craniosynostosis-intracranial calcifications syndrome 0 trials
- Craniotelencephalic dysplasia 0 trials
- Familial scaphocephaly syndrome 0 trials Sub-types →
- Holoprosencephaly-craniosynostosis syndrome 0 trials
- Lethal occipital encephalocele-skeletal dysplasia syndrome 0 trials
- Osteosclerosis-developmental delay-craniosynostosis syndrome 0 trials
- Trigonocephaly-broad thumbs syndrome 0 trials
Isolated craniosynostosis 1 trial · 3 incl. sub-types
4 sub-types
- Isolated oxycephaly 0 trials · 2 incl. sub-types Sub-types →
- Isolated cloverleaf skull syndrome 0 trials
- Isolated trigonocephaly 0 trials Sub-types →
- Non-syndromic unisutural craniosynostosis 0 trials
Craniosynostosis syndrome, autosomal recessive 0 trials · 2 incl. sub-types
2 sub-types
- Antley-Bixler syndrome 2 trials Sub-types →
- Cranioectodermal dysplasia 0 trials Sub-types →
Hordnes Engebretsen Knudtson syndrome 0 trials
Iida Kannari syndrome 0 trials
Craniosynostosis Fontaine type 0 trials
Craniosynostosis Maroteaux Fonfria type 0 trials
Craniosynostosis alopecia brain defect 0 trials
Craniosynostosis arthrogryposis cleft palate 0 trials
Craniosynostosis autosomal dominant 0 trials
Craniosynostosis cleft lip palate arthrogryposis 0 trials
Craniosynostosis contractures cleft 0 trials
Craniosynostosis exostoses nevus epibulbar dermoid 0 trials
Craniosynostosis intellectual disability heart defects 0 trials
Craniosynostosis with ectopia lentis 0 trials
Craniosynostosis with ocular abnormalities and hallucal defects 0 trials
Craniosynostosis, Adelaide type 0 trials
Mehta lewis patton syndrome 0 trials
Non-syndromic bicoronal and metopic craniosynostosis 0 trials
Non-syndromic bicoronal and sagittal craniosynostosis 0 trials
Non-syndromic bilambdoid craniosynostosis 0 trials
Non-syndromic metopic and sagittal craniosynostosis 0 trials
Non-syndromic multisutural craniosynostosis 0 trials
Non-syndromic non-specific multisutural craniosynostosis 0 trials
Non-syndromic unicoronal and sagittal craniosynostosis 0 trials
Non-syndromic unicoronal craniosynostosis 0 trials
Non-syndromic unifrontosphenoidal craniosynostosis 0 trials
Non-syndromic unilambdoid craniosynostosis 0 trials
Non-syndromic unisquamosal craniosynostosis 0 trials

Most studied deeper sub-types

Apert syndrome (11) Saethre-Chotzen syndrome (3) TWIST1-related craniosynostosis (2) Pfeiffer syndrome (1) Acrocephalopolysyndactyly (0) Antley-Bixler syndrome with genital anomalies and disordered steroidogenesis (0) Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis (0) Bazopoulou Kyrkanidou syndrome (0) Carpenter syndrome (0) Cote katsantoni syndrome (0) Cranioectodermal dysplasia 1 (0) Cranioectodermal dysplasia 2 (0) Cranioectodermal dysplasia 3 (0) Cranioectodermal dysplasia 4 (0) Cranioectodermal dysplasia 5 (0) Cranioectodermal dysplasia 6 (0) Craniosynostosis 6 (0) Craniosynostosis-Dandy-Walker malformation-hydrocephalus syndrome (0) Familial scaphocephaly syndrome, McGillivray type (0) FGFR1-related Pfeiffer syndrome (0)

Including sub-types (39) Tagged with Craniosynostosis (17)

Trials to join now! 7 Not yet recruiting 3 Not yet finished but already full! 1 Completed 4 Terminated 2

Craniosynostosis

Where it sits in the disease tree

Most studied deeper sub-types

Tiny trial compares skull surgery techniques for babies

Brain scans reveal how skull surgery affects young Children's neural pathways