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Constitutional megaloblastic anemia with severe neurologic disease

MONDO:0013456

Also known as: DHFR deficiency, dihydrofolate reductase deficiency, megaloblastic anaemia due to dihydrofolate reductase deficiency, megaloblastic anemia due to dihydrofolate reductase deficiency

8 clinical trials for this condition and its sub-types.

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Broader categories

Disease (717) Anemia (252) Metabolic disease (241) Hereditary disease (188) Hematologic disorder (172) Inborn errors of metabolism (47) Human disease (15) Deficiency anemia (3) Disease of genetic or genomic mechanism (2) Hereditary anemia (2)

Trials to join now! 3 Not yet recruiting 2 Not yet finished but already full! 1 Completed 2

New blood treatment could block zika in transfusions

Disease control Ongoing

This study tests a special treatment for red blood cells that aims to kill the Zika virus, making transfusions safer. About 692 people who need blood transfusions will receive either treated or standard blood. The goal is to see if the treated blood works just as well and is safe…

Phase 3 • Sponsor: Cerus Corporation • Aim: Disease control

Last updated Jun 27, 2026 11:03 UTC