Combined immunodeficiency due to DOCK8 deficiency

MONDO:0009478

Combined immunodeficiency due to dedicator of cytokinesis 8 protein (DOCK8) deficiency is a form of T and B cell immunodeficiency characterized by recurrent cutaneous viral infections, susceptibility to cancer and elevated serum levels of immunoglobulin E (IgE).

Also known as: Cid due to DOCK8 deficiency, DOCK8 immunodeficiency syndrome, combined immunodeficiency due to DOCK8 deficiency, combined immunodeficiency due to dedicator of cytokinesis 8 protein deficiency, dedicator of cytokinesis 8 deficiency, AR hyperimmunoglobulin E syndrome, AR-HIES, DOCK8 deficiency

93 clinical trials for this condition and its sub-types.

Follow this condition — get notified about new trials

Broader categories

Disease (618) Hereditary disease (172) Hematologic disorder (160) Immune system disorder (140) Inborn error of immunity (113) Immunodeficiency disease (48) Human disease (14) Leukocyte disorder (5) B cell deficiency (4) Hyper-IgE syndrome (4)

Trials to join now! 49 Not yet recruiting 8 Not yet finished but already full! 10 Completed 25 Terminated 1

Can extra care after transplant help older patients live better?

Disease control Terminated

This study tested two extra care programs—supportive palliative care and clinical management of other health issues—for older or frail patients who had a donor stem cell transplant. The goal was to see if these programs could improve quality of life and survival compared to stand…

Phase: PHASE2, PHASE3 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control

Last updated Jun 27, 2026 08:10 UTC

Combined immunodeficiency due to DOCK8 deficiency

Broader categories

Can extra care after transplant help older patients live better?