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Coloboma
MONDO:0001476An abnormality in which a part of a structure in one or both eyes is missing.
Also known as: coloboma of the eye, ocular coloboma, coloboma of macula, congenital ocular coloboma
15 clinical trials for this condition and its sub-types.
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Broader categories
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VR headsets tested as a possible treatment for blindness
Disease control TerminatedThis study tested whether using a virtual reality headset for one-hour sessions could help regenerate damaged optic nerves and improve vision in people with glaucoma or other retinal diseases. The idea came from promising results in rodents. However, the trial was terminated earl…
Phase: NA • Sponsor: Stanford University • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Promising drug for recurrent brain tumor in kids falls short in early trial
Disease control TerminatedThis study tested an oral drug called CX-4945 (silmitasertib) in 21 children with recurrent SHH medulloblastoma, a rare brain tumor. The trial aimed to find the best dose and see if the drug could shrink tumors. However, the study was stopped early, so we don't have clear answers…
Phase: PHASE1, PHASE2 • Sponsor: Pediatric Brain Tumor Consortium • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC