Classic complement early component deficiency

MONDO:0000015

A genetic deficiency of any early component of the classical pathway (C1q, C1r/s, C2, C4, and C3) that is associated with autoimmune diseases due to the failure of clearance of immune complexes (IC) and apoptotic materials, and the impairment of normal humoral response.

Also known as: genetic deficiency of early component of the classical complement pathway

48 clinical trials for this condition and its sub-types, 0 tagged with Classic complement early component deficiency itself.

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Where it sits in the disease tree

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Part of

↑ Complement deficiency (28)

Sub-types of Classic complement early component deficiency

C1 inhibitor deficiency 5 trials
Complement component 3 deficiency 2 trials
Complement component 2 deficiency 0 trials
Complement component 4a deficiency 0 trials
Complement component 4b deficiency 0 trials
Complement component 5 deficiency 0 trials
Complement component 6 deficiency 0 trials
Complement component 7 deficiency 0 trials
Complement component 9 deficiency 0 trials
Complement component C1r/C1s deficiency 0 trials
Complement component C1s deficiency 0 trials
Type I complement component 8 deficiency 0 trials
Type II complement component 8 deficiency 0 trials

Including sub-types (48) Tagged with Classic complement early component deficiency (0)

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